| Page 138 | Rogel Cancer Center | University of Michigan

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Transgenic Animal Models Established Transgenic Technology Service Highlights Provides deep expertise and specialized equipment Training courses in CRISPR/Cas9-ES Cell and Microinjection Guaranteed production of transgenic founders Unique mouse strains produced from ES cells Production services that include: Novel transgenic mice/rats CRISPR/Cas9 mice/rat knockouts Gene targeted mice with ES cells Non-standard genetic backgrounds Read more about Transgenic Animal Models	Tissue and Molecular Pathology Tissue Procurement and Evaluation Excellence to Support Research Service Highlights Bright-field and multispectral whole slide imaging Tissue procurement Tissue processing, embedding, and sectioning Hematoxylin and eosin staining Special stains Immunohistochemistry — frozen or FFPE, DAKO and Ventana Tissue banking Molecular pathology services Tissue microarray construction Read more about Tissue and Molecular Pathology	Pharmacokinetics Pharmacokinetics Team Helps Advance Discovery Service Highlights Access to state-of-the-art instrumentation for bioanalysis and MS imaging operated by highly-trained technicians Support for drug metabolism and PK of 2600 compounds for drug discovery and development since inception Six patents and $15M in grant funding from joint grant applications with Rogel Cancer Center members Free consultation for Rogel Cancer Center members Read more about Pharmacokinetics	Cell and Tissue Imaging Cell and Tissue Imaging Excellence U-M Biomedical Research Core Facilities Service Highlights Nikon N-SIM Super-Resolution and X1 Yokogawa Spinning Disk Confocal Microscopy (available at the Med Sci II location) Read more about Cell and Tissue Imaging
Bryan J Schneider MD Read more about Bryan J Schneider MD	Leslie Anne Fecher MD Read more about Leslie Anne Fecher MD	Startup with U-M technology goes public Kura Oncology Inc., a clinical stage biopharmaceutical company that develops therapies for cancer patients, is now trading on the NASDAQ after an initial public offering. Read more about Startup with U-M technology goes public	U-M launches new app for breast cancer patients Patients being treated for breast cancer at the University of Michigan Rogel Cancer Center now have a new way to help manage the overload of information and reminders that comes with cancer diagnosis, surgery, chemotherapy or radiation treatment. Read more about U-M launches new app for breast cancer patients
Cancer cells hijack glucose, alter immune cells When cancer cells compete with immune cells for glucose, the cancer wins. As a result, the immune T cells are not healthy and don’t have the weapons to kill the cancer. Read more about Cancer cells hijack glucose, alter immune cells	Immune Monitoring Immune Monitoring Shared Resource Supports University Research Efforts The Immune Monitoring Shared Resource team provides immunologic and biological support for ongoing research projects and clinical trials at the University of Michigan Rogel Cancer Center and the biomedical community at the University of Michigan. Read more about Immune Monitoring

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