| Page 110 | Rogel Cancer Center | University of Michigan

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Developmental Therapeutics Developmental Therapeutics Program Promotes the Advancement of Discoveries The Developmental Therapeutics Program fosters the advancement of University of Michigan Rogel Cancer Center discoveries to translational research. Under the guidance of co-leaders Jolanta Grembecka, Ph.D., and Judith Sebolt-Leopold, Ph.D., the Developmental Therapeutics Program moves basic science discoveries to the preclinical level and aids members in moving their discoveries along the translational pipeline. Read more about Developmental Therapeutics	Cancer Genetics Cancer Genetics Program Produces Innovative Collaborations Cancer Genetics Specific Aims Aim 1: Mechanisms Elucidate the genetic and epigenetic mechanisms of cancer development and progression. Aim 2: Models Utilize novel animal model systems for characterizing the impact of critical genetic alterations found in human cancers. Read more about Cancer Genetics	Cancer Hematopoiesis and Immunology Harnessing Stem and Immune Cell Populations for Cancer Research Cancer Hematopoiesis and Immunology Specific Aims Aim 1: Mechanisms Elucidate molecular mechanisms regulating immune and non-immune hematopoietic cell function during homeostasis, cancer progression and cellular therapy. Aim 2: Crosstalk Understand mechanisms of cross-talk between immune cells and non-immune cells in cancer therapy and HCT. Read more about Cancer Hematopoiesis and Immunology	Signaling and Tumor Microenvironment Signaling and Tumor Microenvironment Program Leads in Translational Cancer Research Signaling and Tumor Microenvironment Program Specific Aims Aim 1: Signaling Elucidate the role of cell fate and plasticity during tissue homeostasis and cancer progression. Aim 2: Microenvironment Define the heterocellular interactions that drive tumor epithelial growth and treatment response. Read more about Signaling and Tumor Microenvironment
Cancer Epidemiology and Prevention The information on this page have been moved to the Cancer Control and Population Sciences page Read more about Cancer Epidemiology and Prevention	Health Behavior and Outcomes The information on this page have been moved to the Cancer Control and Population Sciences page Read more about Health Behavior and Outcomes	Keith Andrew Casper MD Read more about Keith Andrew Casper MD	Jeffrey Scott Moyer MD Read more about Jeffrey Scott Moyer MD
Andrew Gregg Shuman MD Read more about Andrew Gregg Shuman MD	Translational and Clinical Research Providing Scientific Excellence Translational and Clinical Research Specific Aims Aim 1: Molecular Approaches to Patient Care Develop and apply state-of-the-art molecularly targeted approaches to cancer diagnosis and treatment. Read more about Translational and Clinical Research

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