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News Archive

Date: 01/17/2023
Immunotherapy has been a major advancement in cancer therapy, but it is not effective for all patients. In some instances, it can even cause tumors to “hyperprogress.” Researchers from the Rogel Cancer Center have found a mechanism for why a subset of patients’ tumors grow, rather than shrink, when faced with immunotherapy.
Date: 01/12/2023
By capturing and amplifying tiny sound waves created when X-rays heat tissues in the body, medical professionals can map the radiation dose within the body, giving them new data to guide treatments in real time. It’s a first-of-its-kind view of an interaction doctors have previously been unable to "see."
Date: 01/10/2023
Anao Zhang, Ph.D., LCSW, ACSW, ACBT is principal investigator on a new project funded with a $250,000 Eugene Washington PCORI Engagement Award, an initiative of the Patient-Centered Outcomes Research Institute, or PCORI. The research team will build out existing research infrastructure in patient-centered outcomes to enhance participation from AYA cancer survivors who identify as BIPOC or sexual and gender minorities.
Date: 12/28/2022
Most colorectal cancers are insensitive to immune therapies. This research indicates one of the mechanisms leading to this resistance is likely the high level of ammonia that accumulates in the microenvironment.
Date: 12/26/2022
Undergoing emergency surgery was associated with a higher rate of complications, including death. Out of close to 5,000 patients who underwent any type of surgery for colorectal cancer, 23% had emergency surgery -- but those patients made up 63% of the deaths.
Date: 12/09/2022
Researchers at the University of Michigan Rogel Cancer Center and School of Dentistry found that certain drugs can change the fundamental makeup of cancer stem cells in mouse models of mucoepidermoid carcinoma – a lethal form of salivary gland cancer that currently has no treatment options.
Date: 12/07/2022
Rogel Cancer Center faculty and trainees will lead more than two dozen presentations, posters and moderated sessions at the American Society of Hematology annual meeting. This year’s meeting will be held in-person and virtually.
Date: 12/06/2022
Principal investigator Arul Chinnaiyan, M.D., Ph.D., will lead a $4 million project that will employ a suite of cutting-edge drug development techniques to develop an effective inhibitor of MYC, a major driver of about 70% of all cancers, including prostate cancer.
Date: 11/23/2022
As cancers grow and potentially spread to new parts of the body, they often shed cells and DNA into the blood stream. DNA can be analyzed for both the amount of DNA present and whether any potential mutations exist that may aid providers in deciding on treatments. These tests, known as liquid biopsies, have become standard practice for certain types of cancer, especially those for which there are drugs that target distinct DNA mutations. Whether liquid biopsies could help providers understand which patients may do better than others, though, is unknown.
Date: 11/18/2022
As part of its Discovery Science grants program, the American Cancer Society has awarded Rogel Cancer Center researcher Anthony Scott, M.D., $792,000 to look at how genes associated with Lynch syndrome impact cancer developing.

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