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Rogel Cancer Center Researchers Present at AACR Annual Meeting

Date Visible: 
04/11/2023 - 8:30am

Media contact: Anna Megdell, 734-764-2220 |  Patients may contact Cancer AnswerLine 800-865-1125

The 2023 AACR meeting runs from April 14 - 19, 2023

AACR 2023 meeting banner with science imagesCourtesy AACR

Rogel Cancer Center faculty and trainees will lead over two dozen presentations, posters and moderated sessions at the American Association for Cancer Research annual meeting. This year’s meeting will be held in-person.

Check out the list of U-M presenters to support your colleagues. Connect with researchers on Twitter using #AACR23. Be sure to tag @UMRogelCancer.

Presenter information is sometimes incomplete. If your session is missing, please email the abstract link to [email protected].

April 15

ED025 - Innovations in Methods for Adapting and Personalizing Interventions for Cancer Control

Inbal Nahum-Shani, Chair and Presenter
10:00 AM – 11:30 AM
Room W312 - Convention Center

Making phase I trials relevant: Aligning need with design

Thomas M. Braun
10:05 AM – 10:25 AM
Valencia D - Convention Center

Establishment and regulation of the pancreatic cancer microenvironment

Marina Pasca Di Magliano
12:30 PM – 12:50 PM
Tangerine Ballroom 2 (WF2) - Convention Center

April 16

MS.ET09.01 - Small Molecule Therapeutic Agents

Judy Leopold, Chair
3:00 PM – 5:00 PM
Room W224 - Convention Center

1160 - A machine learning based method for in-vivo metabolic flux analysis of patient tumors

Anjali Mittal
4:07 PM – 4:22 PM
Room W304 A-D - Convention Center

Poster Session, 1:30-5:00 PM

994 / 4 - Chiroptical detection and mutation analysis of cancer-associated extracellular vesicles in microfluidic devices with oriented chiral nanoparticles

Abha Kumari
Section 41

1068 / 12 - A precision CRISPR approach to target structural variant junctions in cancer

Radhika Suhas Hulbatte
Section 43

1092 / 5 - Targeting one-carbon metabolism radiosensitizes pancreatic ductal adenocarcinoma cells (PDAC)

Minal Nenwani
Section 44

1093 / 6 - Measuring and inhibiting purine metabolism in patients with glioblastoma

Daniel R. Wahl
Section 44

1095 / 8 - Exploiting altered methionine metabolism to overcome treatment resistance in glioblastoma

Navyateja Korimerla
Section 44

595 / 29 - Targeting metabolic vulnerability in brain-metastatic HER2+ breast cancer

Habib Serhan
Section 20

331 / 11 - Mitochondrial transfer from astrocytes drives glioblastoma tumorigenicity

Dionysios C. Watson
Section 12

April 17

AOS09 - Informing Future Precision Medicine Trials for Pancreatic Cancer

Marina Pasca di Magliano
10:45 AM – 11:05 AM
Valencia BC - Convention Center

SY13 - New Horizons for T Cell Immunity and Checkpoints

Weiping Zou
1:00 PM – 1:20 PM
Tangerine Ballroom 2 (WF2) - Convention Center

MS.CH01.01 - New Targeted Protein Degraders: Discovery and Novel Design Strategies

Yu Chang
3:37 PM – 3:52 PM
Room W224 - Convention Center

MS.MD01.02 - Molecular Pathway Discovery and Translation in Solid Tumors

3:21 PM – 3:36 PM
Weihua Zhou
Room W304 A-D - Convention Center

TM02 - Cancer Immunoprevention: A Cancer Immunology Working Group Town Hall Meeting and Networking Reception

Yu Leo Lei
6:50 PM – 7:00 PM
Windermere X - Hyatt Regency

Poster Session, 9:00 AM - 12:30 PM

2036 / 5 - Distinct mutational processes shape selection of MHC class I and class II mutations across primary and metastatic tumors

Michael Mumphrey
Section 32

2026 / 10 - Comprehensive metabolic flux analysis on triple-negative breast cancer shows potential collaterally lethal targets related to the serine pathway

Jin Heon Jeon
Section 31

2131 / 5 - Immunoaffinity isolation of EpCAM expressing exosomes utilizing high throughput microfluidic chip with IEDDA chemistry (EpCAM-TCOOncoBean Chip)

Nna-Emeka Onukwugha
Section 39

2115 / 18 - Zero-waste molecular diagnostics from biopsy needle wash water

Jack Wadden
Section 38

2256 / 3 - Cancer stem cells and exosomal PD-L1 suppress anti-tumor B cells

Ying Xin
Section 43

2279 / 26 - Tumor treating fields induce immune modulation in non-small cell lung cancer

Suhe Wang
Section 43

2236 / 13 - The role of CPI-613 in cholangiocarcinoma treatment

Fulei Wuchu
Section 42

2244 / 21 - Association of chromosomal instability with poor prognosis in metastatic hormone sensitive and castrate-resistant prostate cancer

Ryan J. Rebernick
Section 42

1679 / 4 - Unraveling the function of TRAF2 and NCK interacting kinase (TNIK) in high-grade serous ovarian cancer

Noah Puleo
Section 19

1685 / 10 - Overcoming acquired resistance to PROTAC degraders

Tongchen He
Section 19

1745 / 10 - Targeting therapeutic resistance of esophageal adenocarcinoma through modulating the epithelial-to-mesenchymal transition via NFκB-mediated signaling

Yun Zhang
Section 21

1570 / 18 - Novel Myc-dependent compound DL78 selectively induces mitotic catastrophe and cell death in high grade serous ovarian cancer

Jessica Teitel
Section 15

1634 / 24 - Novel autophagy inhibitor ESK981 potentiates MEK inhibition cytotoxicity in pancreatic cancer

Caleb Cheng
Section 17

1501 / 28 - Epigenetic dedifferentiation as a therapeutic strategy in adrenal cancer

Dipika R. Mohan
Section 12

1322 / 12 - Comparison of brain extracellular matrices in a blood brain barrier organ on a chip model

Ehsanul Hoque Apu
Section 5

Poster Session, 1:30 PM - 5:00 PM

LB163 / 14 - A microfluidic platform for developing circulating tumor cells (CTCs) organoids for precision medicine in pancreatic cancer

Yu Zhang
Section 36

3297 / 5 - Deep reactive ion etched microneedle array for in-vivo melanoma cancer monitoring via cancer exosome isolation

Scott M. Smith
Section 41

3354 / 29 - Isolation and characterization of circulating tumor cells from ductal carcinoma in situ patients using label free technology

Neha Nagpal
Section 42

CT151 / 13 - A phase II study of optimized individualized adaptive radiation therapy for hepatocellular carcinoma

Daniel J. Herr
Section 47

2820 / 11 - Defining the role of purine metabolism in radiation resistance in H3K27M–mutant diffuse midline glioma

Erik R. Peterson
Section 19

2823 / 14 - Targeting monopolar spindle kinase I (TTK) as a radiosensitizing strategy in syngeneic murine models of triple negative breast cancer (TNBC) and its implications on the tumor immune microenvironment

Kassidy M. Jungles
Section 19

2401 / 1 - Molecular mechanisms of intrinsic radioresistance in breast cancer

Breanna N. McBean
Section 3

April 18

AOS01 - Advances in Brain Tumor Research and Treatment

Carl Koschmann
12:35 PM – 12:55 PM
Room W307 - Convention Center

AACR James S. Ewing-Thelma B. Dunn Award for Outstanding Achievement in Pathology in Cancer Research

Arul M. Chinnaiyan
5:15 PM

Poster Session 9:00 AM - 12:30 PM

4536 / 15 - Investigating the correlation between molecular diagnostics, targeted therapies and treatment outcomes in Rosai Dorfman disease: a single-institution experience

Samuel B. Reynolds
Section 44

3909 / 28 - THY1 regulates therapy resistance in glioblastoma recurrence

Sunita Shankar
Section 16

3677 / 8 - DNA damage signaling activates de novo GTP synthesis to promote chemoradiation resistance in glioblastoma

Andrew J. Scott
Section 7

3550 / 1 - The ENL YEATS domain links leukemic stem cell frequency and enhances YEATS inhibitor sensitivity in MLL-ENL leukemias

Hsiangyu Hu
Section 2

3523 / 3 - A systematic comparison of molecular features shared by H3K27-altered diffuse midline gliomas and posterior fossa A ependymomas

Matthew Pun
Section 1

Poster Session, 1:30 PM - 5:00 PM

LB252 / 4 - HPV integration events are heterogenous, clonally selected and associated with spatially distinct transcriptomic profiles in aggressive HPV positive oropharyngeal squamous cell carcinoma

Wenjin Gu
Section 35

5581 / 5 - Single-cell genomic analysis of patient-derived circulating tumor cells in pancreatic cancer

Harrison Ball
Section 41

5502 / 20 - Androgen blockade confers sensitivity to PIKfyve inhibition in prostate cancer

Yuanyuan Qiao
Section 38

4700 / 13 - Spatial analysis of the immune microenvironment and tumor cell transition in sarcomatoid renal cell carcinoma

Allison May
Section 7

5595 /19 - Serial monitoring of circulating tumor cells and circulating tumor DNA in metastatic lobular breast cancer identifies intra-tumor heterogeneity and precision and immuno-oncology biomarkers of therapeutic importance

Andi Cani
Section 41

5259 / 13 - Bazedoxifene plus conjugated estrogen improves metabolic health and reduces mammary gland epithelial proliferation in an ovary intact rat model of obesity and breast cancer risk

Erin Giles
Section 27

April 19

ADT09 - Technical Advances in Liquid Biopsy and Rare Event Detection

Sunitha Nagrath, Chair and Presenter
10:15 AM – 11:45 AM
Room W414 - Convention Center

Poster Session 9:00 AM - 12:30 PM

6141 / 3 - Mechanisms by which Mito-lonidamine inhibits EGFR mutant lung cancer

Katherine M. Weh
Section 16

6286 / 24 - Targeting Polycomb Repressive Complex 1 with small-molecule inhibitors as a potential therapeutic approach to combat leukemia

Miranda L. Simes
Section 20

6423 / 10 - Targeting an autophagy regulator augments antitumor immunity and immunotherapy

Yi Bao
Section 25

6037 / 10 - Identification of collateral lethal targets in cancers using integrated machine learning and flux analysis platform for personalized metabolic therapy

Abhinav Achreja
Section 11

6529 / 27 - Early life liver proteomic signature and minerals mitigation of liver injury

Muhammad N. Aslam
Section 28

6496 / 17 - Exposure phenotype risk scores (E-PRS) and prostate cancer aggressiveness in the Michigan Genomics Initiative (MGI)

Xinman Zhang
Section 27

5835 / 8 - Targeting discoidin domain receptor 1 (DDR1) reverses glioma immune suppression by remodeling collagen fiber architecture

Syed M. Faisal
Section 3