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Brain Tumor

Discovery of a gene mutation may lead to new treatments for Glioma

A mutated gene affects growth of brain tumor cells in young adults, indicating sensitivity to a new treatment strategy, a team of researchers at the Rogel Cancer Center discovered. These findings, recently published in Cell Reports, present possibilities for more effective therapies for glioma patients with this gene mutation.

Metformin shows promise against rare childhood brain tumor in laboratory studies

Metformin, a drug commonly prescribed against diabetes, holds promise against a rare type of childhood brain tumor in laboratory studies, an international team of researchers led by the Rogel Cancer Center report in Science Translational Medicine.

Targeting a mutation found in all gliomas may be the key immunotherapy success

A common mutation in gliomas sensitizes them to immunotherapy, a finding which researchers believe could have broader therapeutic implications for all glioma patients.

Combination treatment for common glioma type shows promise in mice

These encouraging results, published in the Journal of Clinical Investigation, could be the first step toward developing a treatment for this type of brain cancer.

Glioma Research in Animal Models has Promising Results

A combination approach to treating a prevalent glioma subtype -- including metabolic reprogramming, radiation, chemotherapy and immunotherapy -- led to a complete regression of tumors in 60% of study mice.

Researchers Studying Whether an Anti-Rejection Drug Is Effective Against Glioblastoma

Research led by the Rogel Cancer Center is trying a new approach: Make radiation therapy more effective for glioblastoma patients by targeting a critical metabolic pathway and disrupting its ability to repair the DNA damage caused by the radiation.

Living with Brain Cancer

Andrea Passmore learned she had a brain tumor four days before her 51st birthday. Yet she has ultimately come to see the diagnosis as a kind of gift, an opportunity to share the outpouring of support that she has received during her cancer journey.

Glioblastoma Patient is Beating the Odds

Sixteen months ago, Kathy Bellmore was diagnosed with high-grade glioblastoma multiforme, an aggressive brain tumor with few good treatment options. Her tumor couldn't be operated on, so her doctors didn't think she would live beyond 6 months. She came to the U-M Rogel Cancer Center for a second opinion and is now beating the odds and continuing to make memories.

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