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A Study of APTO-253 HCl in Patients With Relapsed or Refractory Hematologic Malignancies

Protocol

UMCC 2014.083

Purpose

This is a phase 1b study to determine the maximum tolerated dose (MTD), dose limiting toxicity (DLT) and recommended phase 2 dose of APTO-253 HCl in patients with relapsed or refractory hematologic malignancies.

UMCC Principal Investigator

Rhim receives award from Doris Duke Foundation

Patient and Family Advisory Committee

Members of PFAC look at information on the internet

What is a Patient and Family Advisory Committee?

Established in 2011, the Rogel Cancer Center’s Patient and Family Advisory Committee (PFAC), partners patients and families with members of the health care team to provide guidance on how to improve the patient and family experience. Our committee is comprised of:

Breast Density and Breast Cancer Risk

What is Breast Density?

Breast density is defined as the ratio of fat to fibroglandular tissue in the breast.

images of the four types of breast density

Radiologists characterize each mammogram into one of four levels of overall density: almost entirely fatty, scattered areas of fibroglandular density, heterogeneously dense, and extremely dense.

New tech could find tiny RNA cancer beacons in blood

Cancerous tumors cast off tiny telltale genetic molecules known as microRNAs and a team of University of Michigan researchers has come up with an efficient way to detect them in blood.

Wicha appointed to National Cancer Advisory Board

President Barack Obama announced his selection of Max S. Wicha, M.D., as one of five new appointees to the National Cancer Advisory Board.

Clinical Trials Overview

One of the unique benefits of being a University of Michigan patient is access to the latest and most promising therapies for cancer.

Clinical trials are for all levels of conditions… see our clinical trials page.

We also have a number of quality of life studies available.

‘Genomic catastrophe’ may cause normal cells to become cancerous

A new study suggests that fusion of one normal cell with another — as observed in inflammation, infection, and injury from carcinogens — triggers a “genomic catastrophe” that converts normal cells to cancer cells and enables tumors to form.

Highlights from the ASCO annual meeting

 

 

 

Study finds misperceptions about impact of double mastectomy

A survey of women with breast cancer found that nearly half considered having a double mastectomy. But of those who considered it, only 37 percent knew that the more aggressive procedure does not improve survival for women with breast cancer.

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