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Single Cell Analysis Resource

Welcome to the University of Michigan Single Cell Analysis Resource

Co-Directors: Evan T. Keller, DVM, Ph.D. | Sunitha Nagrath, Ph.D.

Managing Director: Ebrahim Azizi, PharmD, Ph.D.

Research Staff for Single Cell Nucleic Acid Analysis:
Greg Shelley, Ph.D. | Shamileh Fouladdel, BPharm

Research Staff for Single Rare Cell Isolation:
Eric Lin, Ph.D. | Aaron Kramer, B.Sc.

The Single Cell Analysis Resource is one of the shared resources at Rogel Cancer Center that will provide experimental and technical services to research community at the University of Michigan to explore molecular aspects of cellular heterogeneity, population diversity, and complexity within seemingly homogeneous single cell samples prepared from tissues, biological fluids (e.g. blood) and cultured cell lines.

Single cell analysis can be challenging but highly informative. The core provides consultation to optimize the chances for a successful experiment.

The core will perform below services:

Support for the Single Cell Analysis Shared Resource is also provided by:

    A) Single cell nucleic acid analyses:

      1) Targeted gene expression analysis

      2) Whole transcriptome analysis

      3) 3'-End transcriptome analysis

      4) DNA sequencing analysis

    B) Rare cell isolation:

      1) Label-Free isolation method

      2) Antibody-based isolation method