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Head and Neck Cancer

Team of Rogel researchers receive $3.4M grant to detect high-risk oral pre-cancers

With a new $3.4 million grant from the National Cancer Institute, a team of Rogel Cancer Center researchers will develop new tools to detect changes in precancerous lesions that are likely to become oral cancers. When detected early, this type of head and neck cancer can be curable.

Quicker detection of HPV-positive head and neck cancer combines clinical and lab-based approaches

Early findings of two studies from the University of Michigan Health Rogel Cancer Center shed light on new ways to anticipate recurrence in HPV-positive head and neck cancer sooner. The papers, published in Cancer and Oral Oncology, offer clinical and technological perspectives on how to measure if recurrence is happening earlier than current blood tests allow, and provide a framework for a new, more sensitive blood test that could help in this monitoring.

Research indicates the P53 gene could be the key to treating salivary gland cancer

Researchers at the University of Michigan Rogel Cancer Center and School of Dentistry found that certain drugs can change the fundamental makeup of cancer stem cells in mouse models of mucoepidermoid carcinoma – a lethal form of salivary gland cancer that currently has no treatment options.

Mid-treatment imaging can be used to de-escalate therapy for oropharynx cancer, leading to fewer side effects

A new phase II trial finds that PET scans obtained before and midway through treatment for p16-positive oropharynx cancer (OPC) can help determine whether a patient can receive a lower dose of radiation therapy in the second half of their treatment course without compromising cancer control.

Researchers find two markers can predict head and neck cancer outcomes

A new study from the University of Michigan Health Rogel Cancer Center finds circulating tumor DNA, or ctDNA, levels can predict as early as two weeks after starting treatment which patients are likely to have good outcomes.

An Adenoid Cystic Carcinoma Survivor Dances Her Stress Away

Celina Pitt was diagnosed with adenoid cystic carcinoma -- a kind of head and neck cancer -- and had a lot of difficulty coping with the side effects from it. She lost much of her sense of smell and taste and it was hard to relax or feel comfortable. And then her husband, Ed, suggested they try dancing.

How Head and Neck Cancer Cells Hijack Nearby Healthy Tissue

A team of scientists affiliated with the led by the University of Michigan Rogel Cancer Center and School of Dentistry, identified a mechanism by which head and neck cancer cells subvert adjacent normal tissue, allowing small clusters of cancer cells to burrow beneath the healthy tissue.

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