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Alfred Edward Chang MD


Dr. Alfred E. Chang is the Hugh Cabot Professor of Surgery. He completed his undergraduate training at Dartmouth College in 1971 and his medical education at Dartmouth Medical School and Harvard Medical School in 1974. His general surgical residency was obtained at Duke University Medical Center (1974-1976) and the Hospital of University of Pennsylvania (1979-1982). Between 1976-1979, he completed a surgical oncology fellowship at the Surgery Branch, National Cancer Institute. After his training, Dr. Chang became a senior investigator at the Surgery Branch, NCI (1982-1987). In 1987, Dr. Chang joined the faculty at the University of Michigan.

Besides the administrative duties involving the U-M Rogel Cancer Center and the Division of Surgical Oncology, Dr. Chang has held several roles in national organizations. He has been a member of the Executive Council of the Society of Surgical Oncology. He has been an American College of Surgeons Governor-at-large for the state of Michigan. He has served as a member of the American College of Surgeons Commission of Cancer. 

Clinical Specialization

Dr. Chang's clinical interests are related to general surgical oncology. He has expertise in the areas of breast cancer, melanoma, sarcomas, liver tumors and colorectal cancer. He has had leadership roles in the University of Michigan Rogel Cancer Center which include: Director of the multidisciplinary Breast Care Center; Director of the Gastrointestinal Oncology Program; Associate Director for Translational Research; and Associate Director for Clinical Affairs. He has also been named as one of the Best Doctors in America consistently every year since 1998.


Medical School or Training
  • Harvard Medical School, 1974
  • National Cancer Institute, Surgery General, MD, 1980
  • University of Pennsylvania Medical Centers, Surgery General, PA, 1982
Board Certification
  • Surgery


Dr. Chang runs a laboratory program that has been externally funded for more than 25 years. His research focuses on tumor immunology and immunotherapy. He is co-Director of the Immunological Monitoring Core of the Cancer Center. In addition, he has trained many fellows in the laboratory and is Program Director for an NIH T32 training grant entitled, "University of Michigan Surgical Oncology Research Training Program." He has been on editorial boards of numerous surgery and oncology journals; and, has edited several major textbooks in Surgery and Oncology. He has been a member of the Experimental Therapeutics 2, the Subcommittee D-Clinical Trials and Clinical Oncology NIH study sections.