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Antiandrogen treatment, however, is associated with heart and neurological problems and didn’t increase survival for men with low PSA levels, a University of Michigan study finds.
More than 100 studies worldwide involving an abnormal modification in the tumor suppressor protein PP2A likely need a second look, research led by the University of Michigan Rogel Cancer Center has found. That’s because a new study suggests that commercially available antibodies used to investigate the modification aren’t fully reliable.
The University of Michigan no longer has any teams competing in STAT Madness. The team led by Costas Lyssiotis, Ph.D. made it to Round 4. We are proud of the research done at the University of Michigan and are particularly proud for those who were recognized in this national competition.
The multi-site phase Ib/II study looked at the combination of the immunotherapy drug pembrolizumab with bevacizumab for metastatic renal cell carcinoma. Pembrolizumab is known commercially as Keytruda and bevacizumab is known as Avastin.
Globally, especially in low- and middle-income countries in Africa, Latin America, the Caribbean and Asia, an estimated 569,847 women were diagnosed with cervical cancer in 2018, with 85% of that burden occurring in low- and middle-income countries.
MI-3454 resulted in complete remission in mouse models. Now, a Phase I clinical trial, using a structurally related analog of the compound, is currently enrolling patients.
Women with early stage breast cancer who test positive for an inherited genetic variant aren’t always receiving cancer treatment that follows current guidelines, a new study finds.
By studying two proteins, WDR5 and p53, researchers hoped to learn how -- or if -- these proteins could influence what stem cells developed into. WDR5 and p53 have long been studied in relation to cancer and this research also shed light on how WDR5 regulates p53 both directly and indirectly. For this reason, the research may also help illuminate an emerging class of anti-cancer drugs, WDR5 inhibitors.
By continuously monitoring the body temperature of mice that had undergone bone-marrow transplants, researchers were able to detect early warning signs of graft-versus-host disease -- a dangerous, sometimes deadly response of the transplanted immune system -- in a simple, non-invasive way.
The stones are Rogel Cancer Center’s way of thanking front line staff; from our custodians to doctors, respiratory therapists to nurses and everyone who comes in every day to help our patients. Learn more
Get Rogel gear
A portion of all sales will help Michigan Medicine in securing much needed PPE, support services for employees, faster testing and other COVID-19 research.