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News Archive

Date: 02/23/2023
Russell Ryan, M.D., an assistant professor in the Department of Pathology at the University of Michigan Medical School and a member of the University of Michigan Health Rogel Cancer Center, and his team used a method called ChIP-Seq to map the regulatory elements that control gene expression in B-cell lymphomas, a cancer of the immune system, in sample B-cell cancer cell lines.
Date: 02/20/2023
Research from the University of Michigan Rogel Cancer Center reveals that the metabolic pathways that make a specific type of T cell function are different than previously believed. The key to this discovery lies in a new methodology developed by Hanna Hong, graduate student in immunology and first author of this study.
Date: 02/13/2023
The protein STAT5 has long been an appealing target against cancer, but after decades of research it was consigned to the “undruggable” category. Now, University of Michigan Rogel Cancer Center researchers have found success with a new approach. By tapping into a cellular garbage disposal function, researchers found they could eliminate STAT5 from cell cultures and mice, setting the stage for potential development as a cancer treatment.
Date: 02/08/2023
Starting this month, the University of Michigan Health Ypsilanti Health Center will be offering onsite mammography screening services through a new mobile mammography unit. This addition to the organization’s ambulatory care services will increase access to cancer care and provide screening opportunities for patients near their homes.
Date: 02/02/2023
Researchers at Baylor College of Medicine, the University of Michigan and collaborating institutions working with animal models of GVHD report that alterations in the gut microbiome are connected to an increase in the oxygen levels in the intestine that follows immune-mediated intestinal damage.
Date: 02/02/2023
When noninvasive sound waves break apart tumors, they trigger an immune response in mice. By breaking down the cell wall “cloak,” the treatment exposes cancer cell markers that had previously been hidden from the body’s defenses, researchers at the University of Michigan have shown. The technique developed at Michigan, known as histotripsy, offers a two-prong approach to attacking cancers: the physical destruction of tumors via sound waves and the kickstarting of the body’s immune response. The research shows the potential for this to become a treatment option for patients without the harmful side effects of radiation and chemotherapy.
Date: 02/01/2023
Five University of Michigan Rogel Cancer Center members were elected as 2022 fellows of the American Association for the Advancement of Science. They are among 17 University of Michigan faculty and staff members elected this year.
Date: 02/01/2023
Patients whose brain tumors have a mutated enzyme called IDH1 typically live longer than those without the mutation. But even as these tumors are initially less aggressive, they always come back. A key reason: The tumors are resistant to radiation treatment and are invasive.
Date: 01/17/2023
Immunotherapy has been a major advancement in cancer therapy, but it is not effective for all patients. In some instances, it can even cause tumors to “hyperprogress.” Researchers from the Rogel Cancer Center have found a mechanism for why a subset of patients’ tumors grow, rather than shrink, when faced with immunotherapy.
Date: 01/12/2023
By capturing and amplifying tiny sound waves created when X-rays heat tissues in the body, medical professionals can map the radiation dose within the body, giving them new data to guide treatments in real time. It’s a first-of-its-kind view of an interaction doctors have previously been unable to "see."