Rogel members present at upcoming AACR meeting

ED006 - Development of chemical probes for target validation in hematologic cancers - Jolanta E. Grembecka

4:00 PM – 4:20 PM, New Orleans Theater C

Posters 12:00-1:00 PM

6366 - A novel small molecule inhibitor of MAPK and PI3K ameliorates disease phenotypes in myelofibrosis - Christopher A. Bonham, et al.

5741 - Characterizing isoform switching events in esophageal adenocarcinoma - Yun Zhang, et al.

6049 - Identifying shared features of low-H3K27me3 pediatric brain tumors - Matthew Pun, et al.

ED028 - Defining the clinical utility of MRD testing: Path to guiding treatment decision making - Daniel F. Hayes

11:00 AM – 11:20 AM, Great Hall BC

ADT12 - Linking glioblastoma purine metabolism and radiation resistance in the laboratory and clinic - Daniel Wahl

1:55 PM – 2:15 PM, Room 243-245

MS.PS01.02 - Molecular Genomics of Cancer Risk and Prognosis - Laura A. Kresty, Chairperson

3:00 PM – 5:00 PM, Room 217-219

PAS03 - Personalized Career Conversations - John M. Carethers, Mentor

5:30 PM – 7:30 PM, Mardi Gras Salon D-E, New Orleans Marriott

Posters 1:30-5:00 PM

LB013 / 1 - Subclonal evolution and expansion of spatially distinct THY1-positive cells is associated with recurrence in glioblastoma - Wajd Al-Holou, et al.

314 / 5 - Amplifying STING activation by cyclic dinucleotide-manganese particles for systemic cancer immunotherapy - Xingwu Zhou, et al.

611 / 21 - Assessment of tumor mutation burden and microsatellite instability by single-cell circulating tumor cell genomic profiling - Andi K. Cani, et al.

21 / 2 - Awareness of HPV and experience with cervical cancer screening in rural Southern Vietnam - Minh Tung Phung, et al.

215 / 13 - MDM2 inhibition as a non-hormone dependent radiosensitizing strategy in p53 wild-type breast cancer models - Charles A. Nino, et al.

216 / 14 - Expression of DNA damage response proteins modifies the efficacy of CDK4/6 inhibitor-mediated radiosensitization in breast cancer models - Kassidy M. Jungles, et al.

ADT10 - Peptide Interaction Inhibitors in Cancer Therapeutics - Tomasz Cierpicki, Chairperson

12:30 PM – 2:00 PM, Room 217-219

ADT10 - Predicting druggability of protein-protein interactions to discover new cancer therapeutics - Tomasz Cierpicki

1:25 PM – 1:45 PM, Room 217-219

2176 - NADPH production and redox homeostasis regulate acinar to ductal metaplasia - Megan Radyk

3:05 PM – 3:20 PM, Room 243-245

PAS05 - Navigating the Path to a Successful Career in Cancer Research - John Carethers, Panelist

7:00 PM – 9:00 PM, Acadia Room, New Orleans Marriott

Posters 1:30-5:00 PM

2018 / 22 - Therapeutic benefit of dual ALK and FAK inhibition in neuroblastoma - Seema Chugh, et al.

2046 / 4 - Potential suppression of B effector cells by exosomal PD-L1 on anti-cancer stem cell immunity - You Qin, et al.

1461 / 5 - ETV6 deficiency and microsatellite enhancers drive transcriptional dysregulation in B-lymphoblastic leukemia - Joshua Goldman

1700 / 17 - Serial monitoring of single-cell circulating tumor cell genomics in metastatic lobular breast cancer to identify precision and immuno-oncology biomarkers with therapeutic implications - Andi K. Cani, et al.

SY47 - Minorities in Cancer Research Scientific Symposium: Opportunities to Leverage Legislation and Policies in Addressing Cancer Disparities - John Carethers, Invited Speaker

10:15 AM – 11:45 AM, Room 220-222

SY29 - The application of artificial intelligence in pathology and issues related to deployment, clinical validation, and regulation - Liron Pantanowitz

1:00 PM – 1:20 PM, Room 343-345

3592 - Targeting SWI/SNF ATPases in enhancer-addicted human cancers - Abhijit Parolia

3:20 PM – 3:35 PM, La Nouvelle Orleans C

FO08 - What Is the Causal Link between Race and Early Onset of Colon Cancer? - John Carethers, Moderator and Presenter

5:00 PM – 6:30 PM, New Orleans Theater A

FO08 - Changing epidemiology of CRC: Genetics, geography, and other sociodemographic risk factors - Elena Stoffel

5:10 PM – 5:25 PM, New Orleans Theater A

Posters 9:00 AM-12:30 PM

2792 / 3 - On-chip evaluation of cancer cell-extracellular vesicle interactions using a novel microfluidic microsystem (CellExoChip) Kruthi Srinivasa Raju, et al. (Yoon-Tae Kang presenting)

CT208 / 8 - Feasibility, acceptability, and evaluation of a self-care app to enhance purposeful living among ovarian cancer patients (NCT04458168) - Aliya Alimujiang, et al.

2697 / 12 - Inhibition of estrogen receptor signaling as a strategy for radiosensitization of ER+ breast cancers - Anna R. Michmerhuizen, et al.

2241 / 23 - Evaluating anal cancer screening approaches in high-risk populations in Puerto Rico - Kandyce G. Keller, et al.

2211 / 11 - Cervical cancer screening and vaccination acceptability and attitudes amongst Arab American women in southeastern Michigan - Lilah Khoja, et al.

2248 / 2 - Environmental factors associated with residual disease after ovarian cancer primary cytoreduction surgery - Minh Tung Phung, et al.

2538 / 5 - Role of Argonaute 2 in regulation of immune microenvironment in pancreatic cancer Jennifer Hon, et al.

2476 / 2 - Spatiotemporal analyses of preclinical glioma models reveal 'oncostreams' as dynamic fascicles regulating tumor mesenchymal transformation, invasion, and malignancy - Andrea Comba, et al.

Posters 1:30-5:00 PM

3383 / 11 - Circular RNAs as non-invasive diagnostic biomarkers for prostate cancer Palak Shah, et al.

3340 / 18 - Small molecule mediated stabilization of PP2A modulates the homologous recombination pathway and potentiates DNA damage-induced cell death - Rita A. Avelar, et al.

3341 / 19 - Synthetic lethality by targeting ribonucleotide reductase in PP2A deficient uterine serous carcinoma - Caitlin M. O’Connor, et al.

3274 / 16 - Targeting NSD family histone methyltransferase activity with irreversible inhibitors - Christina Howard, et al.

3307 / 5 - Multiomics analysis to uncover the mechanism of radiosensitization of AR-positive triple negative breast cancers with AR inhibition - Anna R. Michmerhuizen, et al.

3571 / 21 - Prevention of non-small cell lung cancer with kras mutation using a novel peptide vaccine - Suhe Wang, et al.

2966 / 14 - The epigenetic reader function of the YEATS domain in MLL-ENL fusion critically affects leukemic stem cell frequency in MLL-ENL leukemia - Hsiangyu Hu, et al.

3030 / 18 - Integrated in vitro and in silico screening of breast cancer reveals serine metabolism as a precision oncology target - Mark Daniel Slayton, et al.

3072 / 8 - Functional assays of drug sensitivity in real-time from patient material for precision oncology in bladder cancer - Nathan M. Merrill, et al.

3189 / 16 - Characterization of secretory cues that promote brain metastasis using a microfluidic blood brain niche (BBN) device - Christopher Ryan Oliver, et al.

Posters) 9:00 AM-12:30 PM

3965 / 10 - Histone H3 K27M mediated regulation of cancer cell stemness and differentiation in diffuse intrinsic pontine glioma (DIPG) - Monika Sharma, et al.

3966 / 11 - Targeting DNA repair and survival signaling in diffuse intrinsic pontine gliomas to prevent tumor recurrence - Monika Sharma, et al.

4003 / 25 - Identification of a targeted anti-mitotic agent that degrades Myc and specifically induces cancer cell death - Jessica McAnulty, et al.

4012 / 6 - EGFR inhibition in combination with PI3K/AKT/mTOR and/or Bcl-2 inhibition is a promising novel therapeutic approach for inverted sinonasal papillomas and associated sinonasal carcinomas - Athena M. Apfel, et al.

3936 / 10 - Orally bioavailable 'lymphatropic' kinase inhibitors - Brian D. Ross, et al.