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Treg Cell Activity May Limit Immunotherapy

Regulatory T cells, or Treg cells, work within the immune system to suppress immune function. Cancer immunotherapy treatments work by supercharging the immune system to fight cancer. So when Tregs come in and suppress the immune response, it shuts down the cancer-fighting effect. But eliminating the Tregs doesn’t help. Researchers have tried, but a clinical trial testing that idea showed no benefit to patients.

Naive T-cells May Impact Cancer Immunity and Immunotherapy

Most cancer immunotherapy research has targeted effector T cells, but a new study steps back and considers: What if the problem isn’t with the effector T cells, but starts higher up the cellular chain? And so researchers looked at naive T cells -- a type of immune cell that hasn’t yet been triggered to fight.

How studying normal cells offers insights into how cancer spreads

Healthy cells migrate only under special circumstances, such as in the early development of an embryo or when new skin cells and blood vessels move in to repair a wound. For a cancer cell to gain access to the body’s major highways -- the blood vessels and lymphatic system -- it has to invade through something.

Seminars

Cancer Center Seminars and Events

This calendar only shows dates when events for Cancer Center members and trainees are occurring. If you are interested in seeing a calendar of ALL events, please visit the events calendar.

Immune Cells Help Reverse Chemo Resistance in Ovarian Cancer

New research explains why this difficult-to-treat disease becomes resistant to chemotherapy, suggesting potential future treatment options.

3D Cultured Cells Could Drive Precision Therapy for Cancer Treatment

Honeycomb-like arrays of tiny, lab-grown cancers could one day help doctors zero in on individualized treatments for ovarian cancer, an unpredictable disease that kills more than 14,000 women each year in the United States alone.

Why It's Important to Have a Partner in Cancer Therapy

Research has shown that whether or not a patient is married makes a difference in how well -- or not -- a patient does, including for patients with cancer. What researchers don't understand is exactly why being married makes such a difference.

Integrative Oncology Scholars Program

Applications for the Integrative Scholars Program are no longer being accepted

 

For more information please visit the Integrative Oncology Scholars website. Or, contact them by phone 1-888-603-2533; or email: [email protected].

 

Double Mastectomy May Lead to Missed Work

Women who pursue a more aggressive surgery for early stage breast cancer have nearly eight times the odds of reporting substantial employment disruptions, according to a new study from University of Michigan Rogel Cancer Center researchers.

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