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Bone Marrow Transplant

A solution to bone marrow transplant complications could be potato starch supplements

Experts at the University of Michigan Health Rogel Cancer Center have found a potential solution for preventing a common and dangerous complication in patients that receive stem cell transplants from a donor’s blood or bone marrow.

Gene therapy may prove helpful for blood disorders according to new research

Research from experts at Michigan Medicine, the Children’s Hospital of Philadelphia and Penn Medicine is breaking ground on new ways of treating blood disorders, such as sickle cell anemia, through gene therapy.

Study provides an explanation and potential solution for severe graft-versus-host disease

Researchers at Baylor College of Medicine, the University of Michigan and collaborating institutions working with animal models of GVHD report that alterations in the gut microbiome are connected to an increase in the oxygen levels in the intestine that follows immune-mediated intestinal damage.

Some cancer treatments can cause GI issues for patients, researchers find a hopeful solution

When they are not fighting off diseases and infections, immune T cells can sometimes turn on the gastrointestinal system, causing problems such as autoimmune inflammatory bowel disease, graft-vs.-host disease from a bone marrow transplant or colitis from cancer immune checkpoint blocker therapies.

Interferon increases anti-leukemia effect of bone marrow transplant, reduces recurrence

Rogel Cancer Center researchers have identified a drug that, when given along with a bone marrow transplant, drops the risk of leukemia recurring by 20% among the high-risk patients.

Rogel team receives $11.2M to leverage the microbiome against GVHD

A team of researchers from the Rogel Cancer Center received an $11.2 million grant from the National Heart, Lung and Blood Institute to study how to use the microbiome to limit complications of stem cell transplants for blood cancers and other diseases.

Monitoring Body Temperature Could Provide Early Warning for Graft-Versus-Host-Disease

By continuously monitoring the body temperature of mice that had undergone bone-marrow transplants, researchers were able to detect early warning signs of graft-versus-host disease -- a dangerous, sometimes deadly response of the transplanted immune system -- in a simple, non-invasive way.