skip to main content


Recent high-impact publications from Rogel Cancer Center members; April through June, 2023.

Publications from April

Basic Sciences

Zhu L, Tang Y, Li XY, Kerk SA, Lyssiotis CA, Feng W, Sun X, Hespe GE, Wang Z, Stemmler MP, Brabletz S, Brabletz T, Keller ET, Ma J, Cho JS, Yang J, Weiss SJ. A Zeb1/MtCK1 metabolic axis controls osteoclast activation and skeletal remodeling. EMBO J. 2023 APR 03. PubMed PMID: 36843552; PMCID: PMC10068323. Rogel Shared Resources Used: Cell and Tissue Imaging.

Zhu L, Tang Y, Li XY, Kerk SA, Lyssiotis CA, Sun X, Wang Z, Cho JS, Ma J, Weiss SJ. Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption. J Cell Biol. 2023 APR 03. PubMed PMID: 36880731; PMCID: PMC9998966. Rogel Shared Resources Used: Cell and Tissue Imaging.

Cancer Control and Populations Sciences

Arring N, Friese CR, Ghosh B, Titler M, Hamann H, Percac-Lima S, Dobs AS, Naughton MJ, Mishra P, Simon MA, Chen B, Paskett ED, Ploutz-Snyder RJ, Quinn M, Barton DL. Reaching Populations to Address Disparities in Cancer Care Delivery: Results from a Six-Site Initiative. J Natl Compr Canc Netw. 2023 APR 11. PubMed PMID: 37041010.

Ghazal LV, Abrahamse P, Ward KC, Morris AM, Hawley ST, Veenstra CM. Financial Toxicity and Its Association With Health-Related Quality of Life Among Partners of Colorectal Cancer Survivors. JAMA Netw Open. 2023 APR 03. PubMed PMID: 37022684; PMCID: PMC10080378. Rogel Shared Resources Used: Cancer Data Science.

Khalili M, Leonard KR, Ghany MG, Hassan M, Roberts LR, Sterling RK, Belle SH, Lok AS. Racial Disparities in Treatment Initiation and Outcomes of Chronic Hepatitis B Virus Infection in North America. JAMA Netw Open. 2023 APR 03. PubMed PMID: 37036707; PMCID: PMC10087055.

Stoffel EM, Brand RE, Goggins M. Pancreatic Cancer: Changing Epidemiology and New Approaches to Risk Assessment, Early Detection, and Prevention. Gastroenterology. 2023 APR 01. PubMed PMID: 36804602; PMCID: PMC10243302.

Translational and Clinical Research

Speers CW, Symmans WF, Barlow WE, Trevarton A, The S, Du L, Rae JM, Shak S, Baehner R, Sharma P, Pusztai L, Hortobagyi GN, Hayes DF, Albain KS, Godwin A, Thompson A. Evaluation of the Sensitivity to Endocrine Therapy Index and 21-Gene Breast Recurrence Score in the SWOG S8814 Trial. J Clin Oncol. 2023 APR 017. PubMed PMID: 36649570; PMCID: PMC10082279.


Mohan A, Griffith KA, Wuchu F, Zhen DB, Kumar-Sinha C, Crysler O, Hsiehchen D, Enzler T, Dippman D, Gunchick V, Achreja A, Animasahun O, Choppara S, Nenwani M, Chinnaiyan AM, Nagrath D, Zalupski MM, Sahai V. Devimistat in combination with gemcitabine and cisplatin in biliary tract cancer: Pre-clinical evaluation and phase 1b multicenter clinical trial (BilT-04). Clin Cancer Res. 2023 APR 28. PubMed PMID: 37115501. Rogel Shared Resources Used: Cancer Data Science.

Publications from May

Basic Sciences

Sun X, Zhou X, Lei YL, Moon JJ. Unlocking the promise of systemic STING agonist for cancer immunotherapy. J Control Release. 2023 MAY 01. PubMed PMID: 37001564.

Mota M, Sweha SR, Pun M, Natarajan SK, Ding Y, Chung C, Hawes D, Yang F, Judkins AR, Samajdar S, Cao X, Xiao L, Parolia A, Chinnaiyan AM, Venneti S. Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas. Proc Natl Acad Sci U S A. 2023 MAY 02. PubMed PMID: 37094128; PMCID: PMC10161095. Rogel Shared Resources Used: Proteomics.

Shende VV, Harris NR, Sanders JN, Newmister SA, Khatri Y, Movassaghi M, Houk KN, Sherman DH. Molecular Dynamics Simulations Guide Chimeragenesis and Engineered Control of Chemoselectivity in Diketopiperazine Dimerases. Angew Chem Int Ed Engl. 2023 MAY 08. PubMed PMID: 36610039; PMCID: PMC10159983.

Xu C, Dobson HE, Yu M, Gong W, Sun X, Park KS, Kennedy A, Zhou X, Xu J, Xu Y, Tai AW, Lei YL, Moon JJ. STING agonist-loaded mesoporous manganese-silica nanoparticles for vaccine applications. J Control Release. 2023 MAY 01. PubMed PMID: 36948420; PMCID: PMC10164691. Rogel Shared Resources Used: Flow Cytometry, Immune Monitoring.

Publications from June

Basic Sciences

Wood KB, Comba A, Motsch S, Grigera TS, Lowenstein PR. Scale-free correlations and potential criticality in weakly ordered populations of brain cancer cells. Sci Adv. 2023 JUN 28. PubMed PMID: 37379380; PMCID: PMC10306295.

Conchola AS, Frum T, Xiao Z, Hsu PP, Kaur K, Downey MS, Hein RFC, Miller AJ, Tsai YH, Wu A, Holloway EM, Anand A, Murthy PKL, Glass I, Tata PR, Spence JR. Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung. Proc Natl Acad Sci U S A. 2023 JUN 13. PubMed PMID: 37279279; PMCID: PMC10268599. Rogel Shared Resources Used: Cell and Tissue Imaging, Flow Cytometry, Single Cell Spatial Analysis.

Rajan A, Anhezini L, Rives-Quinto N, Chhabra JY, Neville MC, Larson ED, Goodwin SF, Harrison MM, Lee CY. Low-level repressive histone marks fine-tune gene transcription in neural stem cells. Elife. 2023 JUN 14. PubMed PMID: 37314324; PMCID: PMC10344426. Rogel Shared Resources Used: Flow Cytometry, Single Cell Spatial Analysis.

Procario MC, Sexton JZ, Halligan BS, Imperiale MJ. Single-Cell, High-Content Microscopy Analysis of BK Polyomavirus Infection. Microbiol Spectr. 2023 JUN 15. PubMed PMID: 37154756; PMCID: PMC10269497.

Hu J, Hu B, Xu F, Wang M, Qin C, McEachern D, Stuckey J, Wang S. Precise Conformational Control Yielding Highly Potent and Exceptionally Selective BRD4 Degraders with Strong Antitumor Activity. J Med Chem. 2023 JUN 22. PubMed PMID: 37289649. Shared Resources Used: Pharmacokinetics, Proteomics, Structure and Drug Screening.

Bedran G, Polasky DA, Hsiao Y, Yu F, da Veiga Leprevost F, Alfaro JA, Cieslik M, Nesvizhskii AI. Unraveling the glycosylated immunopeptidome with HLA-Glyco. Nat Commun. 2023 JUN 12. PubMed PMID: 37308510; PMCID: PMC10258777.

Cancer Control and Population Sciences

Feld JJ, King WC, Ghany MG, Chang KM, Terrault N, Perrillo RP, Khalili M, Hinerman AS, Janssen H, Lok AS. Characteristics of Older Patients With Immunotolerant Chronic Hepatitis B Virus Infection. Clin Gastroenterol Hepatol. 2023 JUN 01. PubMed PMID: 35843468; PMCID: PMC10363409.

Onyirioha K, Joshi S, Burkholder D, Yekkaluri S, Parikh ND, Singal AG. Clinical Outcomes of Patients With Suspicious (LI-RADS 4) Liver Observations. Clin Gastroenterol Hepatol. 2023 JUN 01. PubMed PMID: 35413448.


Carpenter ES, Elhossiny AM, Kadiyala P, Li J, McGue J, Griffith BD, Zhang Y, Edwards J, Nelson S, Lima F, Donahue KL, Du W, Bischoff AC, Alomari D, Watkoske HR, Mattea M, The S, Espinoza CE, Barrett M, Sonnenday CJ, Olden N, Chen CT, Peterson N, Gunchick V, Sahai V, Rao A, Bednar F, Shi J, Frankel TL, Pasca di Magliano M. Analysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions. Cancer Discov. 2023 JUN 02. PubMed PMID: 37021392; PMCID: PMC10236159. Shared Resources Used: Cancer Data Science, Cell and Tissue Imaging, Flow Cytometry, Immune Monitoring, Single Cell Spatial Analysis, Tissue and Molecular Pathology.

Nwosu ZC, Ward MH, Sajjakulnukit P, Poudel P, Ragulan C, Kasperek S, Radyk M, Sutton D, Menjivar RE, Andren A, Apiz-Saab JJ, Tolstyka Z, Brown K, Lee HJ, Dzierozynski LN, He X, Ps H, Ugras J, Nyamundanda G, Zhang L, Halbrook CJ, Carpenter ES, Shi J, Shriver LP, Patti GJ, Muir A, Pasca di Magliano M, Sadanandam A, Lyssiotis CA. Uridine-derived ribose fuels glucose-restricted pancreatic cancer. Nature. 2023 JUN 01. PubMed PMID: 37198494; PMCID: PMC10232363. Rogel Shared Resources Used: Cell and Tissue Imaging, Tissue and Molecular Pathology.

Archive of past publications