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Recent high-impact publications from Rogel Cancer Center members.

Publications as of September, 2021

Basic Sciences

Park KS, Nam J, Son S, Moon JJ. Personalized combination nano-immunotherapy for robust induction and tumor infiltration of CD8+ T cells. Biomaterials. (2021) PMID: 33962217; PMCID: PMC8184601.

Shukla S, Ying W, Gray F, Yao Y, Simes ML, Zhao Q, Miao H, Cho HJ, González-Alonso P, Winkler A, Lund G, Purohit T, Kim E, Zhang X, Ray JM, He S, Nikolaidis C, Ndoj J, Wang J, Jaremko Ł, Jaremko M, Ryan RJH, Guzman ML, Grembecka J, Cierpicki T. Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain. Nat Chem Biol. (2021) PMID: 34155404; PMCID: PMC8238916.

Du W, Hua F, Li X, Zhang J, Li S, Wang W, Zhou J, Wang W, Liao P, Yan Y, Li G, Wei S, Grove S, Vatan L, Zgodzinski W, Majewski M, Wallner G, Chen H, Kryczek I, Fang JY, Zou W. Loss of optineurin drives cancer immune evasion via palmitoylation-dependent IFNGR1 lysosomal sorting and degradation. Cancer Discov. (2021) PMID: 33627378; PMCID: PMC8292167.

Venkatesan A, Geng J, Kandarpa M, Wijeyesakere SJ, Bhide A, Talpaz M, Pogozheva ID, Raghavan M. Mechanism of mutant calreticulin-mediated activation of the thrombopoietin receptor in cancers. J Cell Biol. (2021) PMID: 33909030; PMCID: PMC8085772.

Poirion OB, Jing Z, Chaudhary K, Huang S, Garmire LX. DeepProg: an ensemble of deep-learning and machine-learning models for prognosis prediction using multi-omics data. Genome Med. (2021) PMID: 34261540; PMCID: PMC8281595.

Yu L, Myers G, Ku CJ, Schneider E, Wang Y, Singh SA, Jearawiriyapaisarn N, White A, Moriguchi T, Khoriaty R, Yamamoto M, Rosenfeld M, Pedron J, Bushweller JH, Lim KC, Engel JD. An erythroid to myeloid cell fate conversion is elicited by LSD1 inactivation. Blood. (2021) PMID: 34324630.

Pendlebury DF, Zhang J, Agrawal R, Shibuya H, Nandakumar J (DT). Structure of a meiosis-specific complex central to BRCA2 localization at recombination sites. Nat Struct Mol Biol. (2021)PubMed PMID: 34373645.

Luan X, Yuan H, Song Y, Hu H, Wen B, He M, Zhang H, Li Y, Li F, Shu P, Burnett JP, Truchan N, Palmisano M, Pai MP, Zhou S, Gao W, Sun D. Reappraisal of anticancer nanomedicine design criteria in three types of preclinical cancer models for better clinical translation. Biomaterials. (2021) PMID: 34144373.

Kremer DM, Nelson BS, Lin L, Yarosz EL, Halbrook CJ, Kerk SA, Sajjakulnukit P, Myers A, Thurston G, Hou SW, Carpenter ES, Andren AC, Nwosu ZC, Cusmano N, Wisner S, Mbah NE, Shan M, Das NK, Magnuson B, Little AC, Savani MR, Ramos J, Gao T, Sastra SA, Palermo CF, Badgley MA, Zhang L, Asara JM, McBrayer SK, Pasca di Magliano M, Crawford HC, Shah YM, Olive KP, Lyssiotis CA. GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis. Nat Commun. (2021) PMID: 34381026; PMCID: PMC8357841.

Geer MJ, Foucar CE, Devata S, Benitez L, Perissinotti AJ, Marini BL, Bixby D. Clinical availability of ATRA for patients with suspected acute promyelocytic leukemia: why guidelines may not be followed. J Natl Compr Canc Netw. (2021) PMID: 34404029.

Translational and Clinical Research

Nielsen TO, Leung SCY, Rimm DL, Dodson A, Acs B, Badve S, Denkert C, Ellis MJ, Fineberg S, Flowers M, Kreipe HH, Laenkholm AV, Pan H, Penault-Llorca FM, Polley MY, Salgado R, Smith IE, Sugie T, Bartlett JMS, McShane LM, Dowsett M, Hayes DF. Assessment of Ki67 in breast cancer: updated recommendations from the international Ki67 in breast cancer working group. J Natl Cancer Inst. (2021) PMID: 33369635.

Alva AS, Mangat PK, Garrett-Mayer E, Halabi S, Hansra D, Calfa CJ, Khalil MF, Ahn ER, Cannon TL, Crilley P, Fisher JG, Haslem DS, Shrestha S, Antonelli KR, Butler NL, Warren SL, Rygiel AL, Ranasinghe S, Bruinooge SS, Schilsky RL. Pembrolizumab in patients with metastatic breast cancer with high tumor mutational burden: results from the targeted agent and profiling utilization registry (TAPUR) study. J Clin Oncol. (2021) PMID: 33844595.

Archive of past publications


January 21, 2021: collaborative publications

March 25, 2021: Basic Sciences publications

March 30, 2021: Basic Sciences publications

September 30, 2021: Basic Sciences and Translational Research publications


January 26, 2020: Cancer Control and Population Sciences publications

April 22, 2020: Translational and Clinical Research publications

May 8, 2020: Basic Sciences, Cancer Control and Population Sciences publications

May 19, 2020: Basic Sciences publications

May 28, 2020: Basic Sciences publications

June 2, 2020: Basic Sciences, Cancer Control and Population Sciences, Translational and Clinical Research and collaborative publications

June 23, 2020: Basic Sciences publications

July 23, 2020: Basic Sciences and collaborative publications


September 23, 2019: Basic Biology, Cancer Genetics, Health Behaviors and Outcomes, Translational and Clinical Research publications

October 9, 2019: Basic Sciences publications

November 6, 2019: Basic Sciences publications

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